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Mobility of group II introns
The major mobility event of group II introns is homing (or retrohoming), in which the intron inserts site-specifically into intronless sites. For organellar introns, this occurs during crosses between two strains, where one strain contains the intron and the other does not. For bacterial introns, homing occurs when homing site DNA is introduced into a cell expressing the intron.
is also an endonuclease-independent pathway, in which bottom strand cleavage
occurs at the replication fork during DNA replication.
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